(1) sebenzisa "indlela yobunjineli bexabiso" ukuthenga izixhobo, iinkqubo ezithile zilandelayo.Iimfuno ezicacileyo, misela ukukhetha kunye nokuthenga izixhobo - ulwazi lweshishini ekujoliswe kulo (ulwazi lubandakanya: umgaqo-nkqubo wokusebenza, iinjongo zolawulo, ubungakanani bemveliso kunye nolawulo lwelizwe, njl. njl.) - imveliso ekujoliswe kuyo yahlalutywa, uhlalutyo lweemveliso ekujoliswe kuzo zesohlwayo, ezizezi. ukuhlelwa komsebenzi, umsebenzi othile kunye nocacileyo, ngoko, uhlalutyo lomsebenzi wesixhobo kunye neqondo elihambelanayo lemfuno yokwenyani, kuthathelwa ingqalelo isixhobo esisebenzayo, uhlobo logqaliselo olusebenzayo) - inkqubo yovavanyo (ngengxoxo yeqela, iingcali zokucebisa kunye nezinye iindlela zohlalutyo malunga noncedo kunye nokungalunganga kwezixhobo zokuqhuba uhlalutyo lweendleko kwaye, emva koko, ukudibanisa into ephambili, kunye nokuhlelwa), misela injongo yokukhetha nokuthenga.

(2) ukufakwa kunye nokwamkelwa kwezixhobo zamachiza.Ngokungqongqo ngokuhambelana neemfuno ze-GMP kunye neenkqubo ezihambelanayo zokusebenza zofakelo lwezixhobo zonyango kunye nokwamkelwa.Abathathi-nxaxheba baquka: imveliso, ubunjineli, amandla, i-QA kunye neengcali zangaphandle.Inkqubo ethile yile: ukuqinisekiswa kofakelo, ukuqinisekiswa kokusebenza.I-QA inoxanduva lokuhlola nokuqinisekisa iprojekthi ye-GMP, uphicotho-zincwadi kunye nokuqinisekisa.

(3) ulwakhiwo lolwazi.Ngokutsho kwezixhobo ze-technical manual kunye ne-GMP, qhagamshelana neengcali ezifanelekileyo, uqulunqa itheyibhile yokugcina izixhobo kunye nencwadana yobugcisa, kwaye urekhode iinkcukacha zedatha yokugcina yangaphambili, iindlela zokugcina kunye nemiphumo yokugcina, ukwenzela ukuba kukhuthazwe ulwazi kunye nomgangatho wolawulo lwezixhobo zonyango kunye ukugcinwa.

(4) ukuphumeza inkqubo “yeeseshoni ezimbini”.Njengoko ulawulo lwezixhobo zonyango luphawulwa ngobuchule obuqinileyo, iingxaki ezinzima kunye noluhlu olubanzi lweenkalo, kunye nokukhawuleza kunye nokufihla ukusilela kwezixhobo, kufuna ukuba siseke umsebenzi okhawulezayo nofanelekileyo, indlela yokuphendula kunye nokusingatha ukusilela ngexesha elifanelekileyo.I-Shift briefing (ibhekisa ekusetyenzisweni kwemizuzu eli-10 phambi kokuya emsebenzini yonke imihla, ukushwankathela nokuxoxa ngosuku olu-1 phambi komsebenzi kunye nesicwangciso somsebenzi wolu suku) kunye nentlanganiso yeveki yesebe (ukuhlolwa, ukuphonononga ukusebenza kule veki, kule veki ukuxoxa malunga nosuku olu-1 phambi komsebenzi kunye nesicwangciso somsebenzi wolu suku). iingxaki eziphambili, xoxa ngesisombululo, kunye nokuseka isicwangciso somsebenzi kwiveki ezayo), enokuphucula ngokufanelekileyo umgangatho womsebenzi, kubaluleke kakhulu ukunciphisa ingozi efihliweyo yokhuseleko.